2021 – present

Kou S, Leng X, Lou H, Nie H, Zhu Q, “Acoustic Resolution Photoacoustic Doppler Flowmetry for Assessment of Patient Rectal Cancer Blood Perfusion”, J Biomed Opt., In press.

Xue M, Zhang M, Li S, Zou Y, Zhu Q, “Automated pipeline for breast cancer diagnosis using US assisted diffuse optical tomography”, Biomed Opt Express. 2023 Nov 1;14(11):6072-6087. doi: 10.1364/BOE.502244. eCollection 2023 Nov 1. PubMed Link

Q Zhu, Hongbo L, W D Middleton, M Itani, I S Hagemann, A R Hagemann, M J Hoegger, P H Thaker, L M Kuroki, C K McCourt, D G Mutch, M A Powell, C L Siegel, “Characterization of Adnexal Lesions using Photoacoustic Imaging to Improve Ultrasound O-RADS Risk Assessment”, Ultrasound in Obstetrics and Gynecology, 2023 Aug 22. doi: 10.1002/uog.27452. PubMed Link

Zhang M, Li S, Xue M, Zhu Q, “Two-stage classification strategy for breast cancer diagnosis using ultrasound-guided diffuse optical tomography and deep learning”, J Biomed Opt. 2023 Aug; 28(8): 086002. PubMed Link

Luo H, Li S, Kou S, Lin Y, Hagemann IS, Zhu Q, “Enhanced 3D visualization of human fallopian tube morphology using a miniature optical coherence tomography catheter”,
Biomed Opt Express. 2023 Jun 12;14(7):3225-3233. doi: 10.1364/BOE.489708. eCollection 2023 Jul 1. PubMed Link

Lin Y, Kou S, Nie H, Luo H, Eltahir A, Chapman W Jr, Hunt S, Mutch M, Zhu Q, “Deep learning based on co-registered ultrasound and photoacoustic imaging improves the assessment of rectal cancer treatment response”, Biomed Opt Express. 2023 Apr 13;14(5):2015-2027. doi: 10.1364/BOE.487647. PubMed Link

Lin Y, Kou S, Zou Y, Maslov K, Zhu Q, “Cylindrical lens configuration for optimizing light delivery in a curvilinear endocavity photoacoustic imaging system”, Opt Lett. 2023 May 1;48(9):2417-2420. doi: 10.1364/OL.486306. PubMed Link

Zhang M, Xue M, Li S, Zou Y, and Zhu Q, “A Fusion Deep Learning Approach Combining Diffuse Optical Tomography and Ultrasound for Improving Breast Cancer Classification”, Biomedical Optics Express. 2023 Mar 27;14(4):1636-1646. doi: 10.1364/BOE.486292. PubMed Link

Li S, Luo H, Kou S, Hagemann IS, Zhu Q, “Depth-resolved attenuation mapping of the human ovary and fallopian tube using optical coherence tomography”, J Biophotonics. 2023 Mar 14:e202300002. doi: 10.1002/jbio.202300002. PubMed Link

Nie H, Luo H, Chen L, Zhu Q, “A Coregistered Ultrasound and Photoacoustic Imaging Protocol for the Transvaginal Imaging of Ovarian Lesions”,
J Vis Exp. 2023 Mar 3;(193). doi: 10.3791/64864.PMID: 36939255. PubMed Link

2022

Zou Y, Amidi E, Luo H, Zhu Q, “Ultrasound-enhanced Unet model for quantitative photoacoustic tomography of ovarian lesions”, Photoacoustics. 2022 Oct 25;28:100420. doi: 10.1016/j.pacs.2022.100420. eCollection 2022 Dec.PMID: 36325304 Free PMC article.  PubMed Link

Leng X, Kou S, Lin Y, Hagemann AR, Hagemann IS, Thaker PH, Kuroki LM, McCourt CK, Mutch DG, Siegel C, Powell MA, Zhu Q., “Quantification of ovarian lesion and fallopian tube vasculature using optical-resolution photoacoustic microscopy”, Sci Rep. 2022 Sep 23;12(1):15850. doi: 10.1038/s41598-022-19778-1.PMID: 36151126. PubMed Link

Li S, Zhang M, Xue M, Zhu Q., “Difference imaging from single measurements in diffuse optical tomography: a deep learning approach”,
J Biomed Opt. 2022 Aug;27(8):086003. doi: 10.1117/1.JBO.27.8.086003.PMID: 36008881 Free PMC article. PubMed Link

Zhu Q, “A review of co-registered transvaginal photoacoustic and ultrasound imaging for ovarian cancer diagnosis”, Current Opinion in Biomedical Engineering, April 2022 ScienceDirect Link

Luo H, Li S, Zeng Y, Cheema H, Otegbeye E, Ahmed S, Chapman WC Jr, Mutch M, Zhou C, Zhu Q, “Human colorectal cancer tissue assessment using optical coherence tomography catheter and deep learning”, J Biophotonics. 2022 Feb 11:e202100349. doi: 10.1002/jbio.202100349. Online ahead of print.PMID: 35150067 PubMed Link

2021

Poplack SP, Young CA, Hagemann IS, Luo J, Herman CR, Wiele K, Li S, Zeng Y, Covington MF, Zhu Q, “Prospective assessment of adjunctive ultrasound-guided diffuse optical tomography in women undergoing breast biopsy: Impact on BI-RADS assessments”, Eur J Radiol. 2021 Nov 13;145:110029. doi: 10.1016/j.ejrad.2021.110029. Online ahead of print.PMID: 34801874 PubMed Link

Zhang M, Li S, Zou Y, Zhu Q, “Deep learning-based method to accurately estimate breast tissue optical properties in the presence of the chest wall”, J Biomed Opt. 2021 Oct;26(10):106004. doi: 10.1117/1.JBO.26.10.106004.PMID: 34672146 Free PMC article. PubMed Link

Leng X, Amidi E, Kou S, Cheema H, Otegbeye E, Chapman WJr, Mutch M, Zhu Q, “Rectal cancer treatment management: deep-learning neural network based on photoacoustic microscopy image outperforms histogram-feature-based classification”, Front Oncol. 2021 Sep 23;11:715332. doi: 10.3389/fonc.2021.715332. eCollection 2021.PMID: 34631543 PubMed Link

Zou Y, Zeng Y, Li S, Zhu Q, “Machine learning model with physical constraints for diffuse optical tomography”, Biomedical Optics Express. 2021 Aug 23;12(9):5720-5735. doi: 10.1364/BOE.432786. eCollection 2021 Sep 1.PMID: 34692211 Free PMC article. PubMed Link

Li S, Menghao Z, Zhu Q, “Ultrasound segmentation-guided edge artifact reduction in diffuse optical tomography using connected component analysis”, Biomedical Optics Express 12(8) 5320-5336, 2021 PubMed Link

Yang G, Huang H, Luo H, Kou S, Amidi E, Achilefu S, Zhu Q, “Fiber endface photoacoustic generator for quantitative photoacoustic tomography”, Opt Lett. 2021 Jun 1;46(11):2706-2709. doi: 10.1364/OL.426033. PubMed Link

Zhu Q, Ademuyiwa FO, Young C, Appleton C, Covington M. F, Ma C, Sanati S, Hagemann IS, Mostafa A, Shihab Uddin SKM, Grigsby I, Frith AE, Hernandez-Aya LF, Poplack SP, “Early Assessment Window for Predicting Breast Cancer Neoadjuvant Therapy using Biomarkers, Ultrasound, and Diffuse Optical Tomography”, Breast Cancer Research and Treatment, 2021 Aug;188(3):615-630. doi: 10.1007/s10549-021-06239-y. Epub 2021 May 10.PMID: 33970392. PubMed Link

Yang G, Amidi E, Zhu Q, “Photoacoustic tomography reconstruction using lag-based delay multiply and sum with a coherence factor improves in vivo ovarian cancer diagnosis”, Biomed. Opt. Express 12(4), 2250-2263 (2021) PubMed Link

Leng, X; Uddin, S; Chapman, WC ; Luo, H; Kou, S; Amidi, E; Yang, G; Chatterjee, D; Shetty, A; Hunt, S; Mutch, M; Zhu, Q, “Assessing rectal cancer treatment response using co-registered endorectal photoacoustic and ultrasound imaging paired with deep learning”, Radiology.   PubMed Link

Li S, Huang K, Zhang M, Uddin S, Zhu Q, “Effect and correction of optode coupling errors in breast imaging using diffuse optical tomography”, Biomed. Opt. Express 12(2), 689-704, 2021  PubMed Link

2015 – 2020

2020

Amidi E, Yang G, Uddin S, Luo H, Middleton W, Powell M, Siegel C, Zhu Q, “Role of blood oxygenation saturation in ovarian cancer diagnosis using multi-spectral photoacoustic tomography”, J Biophotonics. 2020 Dec 30:e202000368. doi: 10.1002/jbio.202000368. Online ahead of print.PMID: 33377620 PubMed Link

Zeng Y, Chapman WC Jr, Lin Y, Li S, Mutch M, Zhu Q, “Diagnosing colorectal abnormalities using scattering coefficient maps acquired from optical coherence tomography”, J Biophotonics. 2020 Oct 16:e202000276. doi: 10.1002/jbio.202000276. Online ahead of print.PMID: 33064368 PubMed Link

Newcomer E, Yang G, Sun B, et al. “Laser Effects in Live Mouse Blastocysts: Pilot Safety Studies of DNA Damage from Photoacoustic Imaging Doses”, F&S Science, 2020 Aug;1(1):53-58. doi: 10.1016/j.xfss.2020.07.001. Epub 2020 Jul 14 PubMed Link

Zhu Q, Poplack S, “A review of optical breast imaging: multi-modality systems for breast cancer diagnosis”, European Journal of Radiology, 2020 Aug;129:109067. doi: 10.1016/j.ejrad.2020.109067. Epub 2020 May 18 PubMed Link

ZHANG M, UDDIN S, LI S, ZHU Q, “Target depth-regularized reconstruction in diffuse optical tomography using ultrasound segmentation as prior information”, Biomedical Optics Express, 2020 May 28;11(6):3331-3345. doi: 10.1364/BOE.388816. eCollection 2020 Jun 1 PubMed Link

Uddin S, Zhang M, Anastasio M, Zhu Q, “Optimal breast cancer diagnostic strategy using combined ultrasound and diffuse optical tomography”, Vol. 11, No. 5, May 2020, Biomedical Optics Express PubMed Link

Li S, Zeng Y, Chapman WC Jr, Erfanzadeh M, Nandy S, Mutch M, Zhu Q, “Adaptive Boosting (AdaBoost)-based multi-wavelength spatial frequency domain imaging and characterization for ex vivo human colorectal tissue assessment”, Journal of Biophotonics, June 2020. Published online March 3, 2020 PubMed Link

Luo H, Yang G, Zhu Q, “Fiber endface illumination diffuser for endo-cavity photoacoustic imaging”, Opt Lett. 2020 Feb 1;45(3):632-635. doi: 10.1364/OL.379844. PMID:32004270 PubMed Link

Zeng Y, Xu S, Chapman Jr. W, Li S, Alipour Z, Abdelal H, Chatterjee D, Mutch M, Zhu Q, “Real-time colorectal cancer diagnosis using PR-OCT with deep learning”, Theranostics 2019, doi:10.7150/thno.40099

Yang G, Amidi E, Chapman Jr. W, Nandy S, Mostafa A, Abdelal H, Alipour Z, Chatterjee D, Mutch M, Zhu, Q, “Co-registered Photoacoustic and Ultrasound Imaging of Human Colorectal Cancer”, J. Biomed Optics, 2019 Nov;24(12):1-13. doi: 10.1117/1.JBO.24.12.121913.

Rao B, Leng X, Zeng Y, Lin Y, Chen R, Zhu Q, Hagemann AR, Kuroki LM, McCourt CK, Mutch DG, Powell MA, Hagemann IS, Zhu Q, “Optical Resolution Photoacoustic Microscopy of Ovary and Fallopian Tube”, Sci Rep. 2019 Oct 4;9(1):14306. doi: 10.1038/s41598-019-50743-7.

Zeng Y, Nandy S, Rao B, Li S, Hagemann AR, Kuroki LK, McCourt C, Mutch DG, Powell MA, Hagemann IS, Zhu Q, “Histogram Analysis of en face Scattering Coefficient Map Predicts Malignancy in Human Ovarian Tissue”, J Biophotonics. 2019 Jul 14:e201900115. doi: 10.1002/jbio.201900115.

Erfanzadeh M and Zhu Q, “Photoacoustic imaging with low-cost sources; a review”, Photoacoustics, 2019 Feb 19;14:1-11. doi: 10.1016/j.pacs.2019.01.004. eCollection 2019 Jun. Review

Uddin S, Zhu Q, “Reducing image artifact in diffuse optical tomography by iterative perturbation correction based on multiwavelength measurements”, J Biomed Opt. 2019 May;24(5):1-8. doi: 10.1117/1.JBO.24.5.056005.

Wang L, Dietz C, Zhou F, Erfanzadeh M, Zhu Q, Smith MB, Yao X, “Sure hunt for peptides with undefined chemical modifications: Proteomics identification of differential albumin adducts of 2-nitroimidazole-indocyanine green in hypoxic tumor”, J Mass Spectrom. 2019 May 25. doi: 10.1002/jms.4376.

Xu S, Uddin S, and Zhu Q, “Improving DOT reconstruction with a Born iterative method and US-guided sparse regularization”, Biomedical Optics Express. Biomed Opt Express. 2019 Apr 22;10(5):2528-2541. doi: 10.1364/BOE.10.002528. eCollection 2019 May 1.

Amidi E, Mostafa A, Nandy S, Yang G, Middleton W, Siegel S, and Zhu Q, “Classification of human ovarian cancer using functional, spectral, and imaging features obtained from in vivo photoacoustic imaging”, Biomed Opt Express. 2019 Apr 8;10(5):2303-2317. doi: 10.1364/BOE.10.002303. eCollection 2019 May 1.

Zeng Y, Rao B, Chapman Jr. W, Nandy S, Rais R, González I, Chatterjee D, Mutch M, Zhu Q, “The Angular Spectrum of the Scattering Coefficient Map Reveals Subsurface Colorectal Cancer”, Scientific Reports, 2019 Feb 28;9(1):2998. doi: 10.1038/s41598-019-39146-w.

2018

Yang G, Amidi E, Nandy S, Mostafa A, Zhu Q “Optimized light delivery probe using ball lenses for co-registered photoacoustic and ultrasound endo-cavity subsurface imaging”, Photoacoustics, Dec. 2018 DOI: 1016/j.pacs.2018.12.001

Erfazandeh M, Nandy S, Kumavor PD, and Zhu Q, “Low-cost compact multispectral spatial frequency domain imaging prototype for tissue characterization”, Biomed Opt Express. 2018 Oct 17;9(11):5503-5510. doi: 10.1364/BOE.9.005503. eCollection 2018 Nov 1

Vavadi H, Mostafa A, Zhou F, Uddin S, Althobaiti M, Xu C, Bansal B, Ademuyiwa F, Poplack S, Zhu Q, “A compact Ultrasound-guided diffuse optical tomography system for breast cancer imaging”, J. Biomed. Opt, J Biomed Opt. 2018 Oct;24(2):1-9. doi: 10.1117/1.JBO.24.2.021203

Leng X, Chapman W, Rao B, Nandy S, Chen R, Rais R, Gonzalez I, Zhou Q, Chatterjee D, Mutch M, Zhu Q, “Feasibility of co-registered Ultrasound and Acoustic-resolution photoacoustic imaging of human colorectal cancer”, Biomed Opt Express. 2018 Oct 3;9(11):5159-5172. doi: 10.1364/BOE.9.005159. eCollection 2018 Nov 1

Althobaiti M, Vavadi H, Zhu Q, “An automated preprocessing method for Diffuse Optical Tomography to improve breast cancer diagnosis”,  Technol Cancer Res Treat. 2018 Jan 1;17:1533033818802791. doi: 10.1177/1533033818802791.

Nandy S, Mostafa A, Hagemann IS, Powell MA, Amidi E, Robinson K, Mutch DG, Siegel C, Zhu Q, “Evaluation of Ovarian Cancer: Initial Application of Coregistered Photoacoustic Tomography and US”, Radiology. 2018 Sep 11:180666. doi: 10.1148/radiol.2018180666.

Nandy S, Chapman W, Rais R, González I, Chatterjee D, Mutch M, Zhu Q, “Label free quantitative optical assessment of human colon tissue using spatial frequency domain imaging”, Techniques in Coloproctology, August 2018, Volume 22, Issue 8, pp 617–621

Zhu Q, Tannenbaum S, Kurtzman S, DeFusco P, Ricci A, Vavadi H, Zhou F, Xu C, Merkulov A, Hegde P, Kane M, Wang L, Sabbath K, “Identifying an early treatment window for predicting breast cancer response to neoadjuvant chemotherapy using immunohistopathology and hemoglobin parameters”, Breast Cancer Res. 2018 Jun 14;20(1):56. doi: 10.1186/s13058-018-0975-1.

Nandy S, Hagemann I, Powell M, Siegel C, Zhu Q, “Quantitative multispectral ex vivo optical evaluation of human ovarian tissue using spatial frequency domain imaging”, Biomedical Optics Express Vol. 9, Issue 5, pp. 2451-2456 (2018)

2017

Erfanzadeh M, Kumavor PD, Zhu Q, “Laser scanning laser diode photoacoustic microscopy system.”, Photoacoustics. 2017 Nov 13;9:1-9. doi: 10.1016/j.pacs.2017.10.001.

Mostafa A, Vavadi H, Uddin S, Zhu Q, “Diffuse optical tomography using semiautomated coregistered ultrasound measurements,” J. Biomed. Opt. 22(12), 121610 (2017), doi: 10.1117/1.JBO.22.12.121610.

Saha D, Tannenbaum S, Zhu Q, “Treatment of Male Breast Cancer by Dual Human Epidermal Growth Factor Receptor 2 (HER2) Blockade and Response Prediction Using Novel Optical Tomography Imaging: A Case Report.”, Cureus. 2017 Jul 17;9(7):e1481. doi: 10.7759/cureus.1481.

Uddin S, Mostafa A, Anastasio A, Zhu Q, “Two step imaging reconstruction using truncated pseudoinverse as a preliminary estimate in ultrasound guided diffuse optical tomography”, Biomed. Opt. Express 8(12), 5437-5449 (2017)

Zhou F, Mostafa A, Zhu Q, “Improving Breast Cancer Diagnosis by Reducing Chest Wall Effect in Diffuse Optical Tomography”, J Biomed Opt. 2017 Mar 1;22(3):36004. doi: 10.1117/1.JBO.22.3.036004.

Althobaiti M, Vavadi H, Zhu Q, “A Diffuse Optical Tomography Reconstruction Method Using Ultrasound Images as Prior for Regularization Matrix”, J Biomed Opt. 2017 Feb 1;22(2):26002. doi: 10.1117/1.JBO.22.2.026002.

Luciano M, Erfanzadeh M, Zhou F, Zhu H, Bornhütter T, Röder B, Zhu Q, Brückner C, “In vivo photoacoustic tumor tomography using a quinoline-annulated porphyrin as NIR molecular contrast agent”, Org Biomol Chem. 2017 Jan 25;15(4):972-983. doi: 10.1039/c6ob02640k.

2016

Nandy S, Sanders M, Zhu Q, “Classification and analysis of human ovarian tissue using full field optical coherence tomography”, Biomed. Opt. Express. 2016 Dec 1; 7(12), 5182-5187.

Nandy S, Mostafa A, Kumavor PD, Sanders M, Brewer M, Zhu Q, “Characterizing optical properties and spatial heterogeneity of human ovarian tissue using spatial frequency domain imaging.”, J Biomed Opt. 2016 Oct;21(10):101402.

Vavadi H, Zhu Q, “Automated data selection method to improve robustness of diffuse optical tomography for breast cancer imaging”, Biomed Opt Express. 2016 Sep 14;7(10):4007-4020.

Zhu Q, Ricci A, Hegde P, Kane M, Cronin E, Merkulov A, Xu Y, Tavakoli B, Tannenbaum S, “US-guided diffuse optical tomography: assessing functional differences in malignant and benign breast lesions and improving diagnostic accuracy in conjunction with conventional US”, Radiology 2016 Aug; 280(2):387-97.

Salehi HS, Li H, Merkulov A, Kumavor PD, Vavadi H, Sanders M, Kueck A, Brewer MA, Zhu Q, “Coregistered photoacoustic and ultrasound imaging and classification of ovarian cancer: ex vivo and in vivo studies.”, J Biomed Opt. 2016 Apr 30;21(4):46006.

Abuteen A, Zhou F, Dietz C, Mohammad I, Smith M, Zhu Q, “Synthesis of a 4-Nitroimidazole Indocyanine Green, Dyes and Pigments”, Dyes and Pigments 126 (March 2016) 251-260

Alqasemi U, Salehi HS, Zhu Q, “Method for estimating closed-form solutions of the light diffusion equation for turbid media of any boundary shape.”, J Opt Soc Am A Opt Image Sci Vis. 2016 Feb 1;33(2):205-13.

2015

Zhou F, Zanganeh S, Mohammad I, Christopher Dietz C, Abuteen A., Smith M, Zhu Q, “Targeting Tumor Hypoxia: A Third Generation 2-Nitroimidazole–Indocyanine Dye–Conjugate with Improved Fluroescent Yield”, Royal Society of Chemistry, 2015 Dec 14;13(46):11220-7. doi: 10.1039/c5ob01460c. (Impact factor 3.820)

Salehi H, Kumavor PD, Li H, Alqasemi U, Wang T, Xu C, Zhu Q, “Design of optimal light delivery system for co-registered transvaginal ultrasound and photoacoustic imaging of ovarian tissue”, Photoacoustics, Volume 3, Issue 3, September 2015, Pages 114-122 (Impact factor 4.6)

Nandy S, Salehi HS, Wang T, Wang X, Sanders M, Kueck A, Brewer M, Zhu Q, “Correlating optical coherence elastography based strain measurements with collagen content of the human ovarian tissue”, Biomed Opt Express. 2015 Sep 3;6(10):3806-11.

Salehi H, Kumavor PD, Li H, Alqasemi U, Wang T, Xu C, Zhu Q, “Design of optimal light delivery system for co-registered transvaginal ultrasound and photoacoustic imaging of ovarian tissue”, Photoacoustics, 2015 Aug 17;3(3):114-22.

Wang R, Li R, Lei Y, Zhu Q, “Tuning to optimize SVM approach for assisting ovarian cancer diagnosis with photoacoustic imaging.”, Biomed Mater Eng. 2015;26 Suppl 1:S975-81.

Xu Y, Zhu Q, “Estimation and imaging of breast lesions using a two-layer tissue structure by ultrasound-guided optical tomography.”, J Biomed Opt. 2015 Jun;20(6):066002. doi: 10.1117/1.JBO.20.6.066002

Xu C, Vavadi H, Merkulov A, Li H, Erfanzadeh, M, Mostafa A, Gong Y, Hassan Salehi H, Tannenbaum S, Zhu Q, “Ultrasound-guided Diffuse Optical Tomography for Predicting and Monitoring Neoadjuvant Chemotherapy of Breast Cancers: Recent Progress”, Ultrasonic Imaging, April 17, 2015

2011-2014

Wang T, Nandy S, Salehi HS, Kumavor PD, Zhu Q, “A low-cost photoacoustic microscopy system with a laser diode excitation”, Biomedical Optics Express, Vol. 5, Issue 9, pp. 3053-3058 (2014)

Alqasemi U, Li H, Yuan G, Kumavor PD, Zanganeh S, Zhu Q, “Interlaced photoacoustic and ultrasound imaging system with real-time co-registration for ovarian tissue characterization”, J Biomed Opt. 2014 Jul;19(7):76020. doi: 10.1117/1.JBO.19.7.076020

Salehi HS, Wang T, Kumavor PD, Li H, Zhu Q, “Design of miniaturized illumination for transvaginal co-registered photoacoustic and ultrasound imaging”, Biomedical Optics Express, Vol. 5, Issue 9, pp. 3074-3079 (2014)

Zhu Q, Wang L, Tannenbaum S, Ricci A, DeFusco P, Hegde P, “Pathologic response prediction to neoadjuvant chemotherapy utilizing pretreatment near infrared imaging parameters and tumor pathologic criteria”, Breast Cancer Res. 2014 Oct 28;16(5):456

Yuan G, Alqasemi U, Chen A, Yang Y, Zhu Q, “Light-emitting diode-based multiwavelength diffuse optical tomography system guided by ultrasound.”, J Biomed Opt. 2014 Dec 1;19(12):126003. doi: 10.1117/1.JBO.19.12.126003

Wang T, Brewer M, Zhu Q, “An overview of optical coherence tomography for ovarian tissue imaging and characterization.”, Nanomed Nanobiotechnol. 2014 Oct 20

Li H, Kumavor P, Alqasemi U, Zhu Q, “Utilizing spatial and spectral features of photoacoustic imaging for ovarian cancer detection and diagnosis.”, J. Biomed Opt. 2014; Jan;20(1):016002. doi: 10.1117/1.JBO.20.1.016002.

2013

Tavakoli B, Zhu Q, “A Two-step Reconstruction Method using Global Optimization and Conjugate Gradient for Ultrasound-guided Diffuse Optical Tomography”, J. Biomed. Optics, January 2013

Zhu Q, DeFusco P, Ricci A Jr, Cronin E, Hegde P, Kane M, Tavakoli B, Xu Y, Hart J, Susan T, “Assessing Breast Tumor Response to Neoadjuvant Chemotherapy using Ultrasound-guided Near Infrared Tomography”, Radiology, February 2013

Wang T, Yang Y, Zhu Q, “A three-parameter logistic model to characterize ovarian tissue using polarization-sensitive optical coherence tomography”, Biomed Opt Express. 2013 Apr 29;4(5):772-7

Kumavor PD, Alqasemi U, Tavakoli B, Li H, Yang Y, Sun X, Warych E, Zhu Q, “Co-registered Pulse-Echo/Photoacoustic Transvaginal Probe for Real Time Imaging of Ovarian Tissue”, J Biophotonics. 2013 Jun;6(6-7):475-484

Xu Y, Zanganeh S, Mohammad I, Aguirre A, Wang T, Yang Y, Kuhn L, Smith MB, Zhu Q, “Targeting tumor hypoxia with 2-nitroimidazole-indocyanine green dye conjugates”, Biomed Opt. 2013 Jun;18(6):66009

Zanganeh S, Li H, Kumavor PD, Alqasemi U, Aguirre A, Mohammad I, Stanford C, Smith MB, Zhu Q, “Photoacoustic imaging enhanced by ICG conjugated single wall carbon nanotubes”, J Biomed Opt. 2013 Sep;18(9):096006

Wang T, Yang Y, Alqasemi U, Kumavor PD, Wang X, Sanders M, Brewer M, Zhu Q, “Characterization of ovarian tissue based on quantitative analysis of photoacoustic microscopy images”, Biomed Opt. Express. 2013 Nov 6;4(12):2763-8. doi: 10.1364/BOE.4.002763

Abuteen A, Zanganeh S, Akhigbe J, Samankumara L, Aguirre A, Biswal N, Braune M, Vollertsen A, Rder B, Brckner C, Zhu Q, “The Evalution of NIR-Absorbing Porphyrin Derivatives as Contrast Agents in Photoacoustic Imaging”, Journal of Physical Chemistry Chemical Physics, 2013 Nov 14;15(42):18502-9

Xu C, Kumavor PD, Alqasemi U, Li H, Xu Y, Zanganeh S, Zhu Q, “Indocyanine green enhanced co-registered diffuse optical tomography and photoacoustic tomography”, J Biomed Opt. 2013 Dec 1;18(12):126006. doi: 10.1117/1.JBO.18.12.126006.

Mohammad I, Stanford C, Morton M, Zhu Q, Smith MB, “Structurally modified indocyanine green dyes. Modification of the polyene linker”, Dyes and Pigment, 99 (2013) 275-283

Zanganeh S, Xu Y, Hamby CV, Backer MV, Backer JM, Zhu Q, “Enhanced fluorescence diffuse optical tomography with indocyanine green-encapsulating liposomes targeted to receptors for vascular endothelial growth factor in tumor vasculature”, J Biomed Opt. 2013 Dec 18(12):126014

Nandy S, Salehi HS, Wang T, Wang X, Sanders M, Kueck A, Brewer M, Zhu Q, “Correlating optical coherence elastography based strain measurements with collagen content of the human ovarian tissue”, Biomed Opt. Express. 2013

2012

Wang T, Kumavor PD, Zhu Q, “Application of laser pulse stretching scheme for efficiently delivering laser energy in photoacoustic imaging”, Journal of Biomedical Optics, 2012 Jun;17(6):061218

Xu C, Kumavor PD, Aguirre A, Zhu Q, “Investigation of a Diffuse Optical Measurements-Assisted Quantitative Photoacoustic Tomography in Reflection Geometry”, Journal of Biomedical Optics, 2012 Jun;17(6):061213

Alqasemi U, Li H, Aguirre A, Zhu Q, “FPGA-based Reconfigurable Processor for Ultrafast Interlaced Ultrasound and Photoacoustic Imaging”, IEEE Transaction on Ultrasonic, Ferroelectrics and Frequency Control 2012 Jul;59(7):1344-53

Yi Yang, Wang T, Xiaohong Wang, Melinda Sanders, Molly Brewer, Zhu Q, “Quantitative analysis of estimated scattering coefficient and phase retardation for ovarian tissue characterization”, 1 July 2012 / Vol. 3, No. 7 / BIOMEDICAL OPTICS EXPRESS 1548

Yang Y, Li X, Wang T, Brewer M, Zhu Q, “Quantitative analysis of angle-resolved scattering properties of ovarian tissue using optical coherence tomography”, Journal of Biomedical Optics, 2012 Sep 28;17(9):90503-1

Alqasemi U, Kumavor PD, Aguirre A, Zhu Q, “Recognition algorithm for assisting ovarian cancer diagnosis from coregistered ultrasound and photoacoustic images: ex vivo study”, Journal of Biomedical Optics, 2012 Dec 1;17(12):126003

2011

Aguirre A, Ardeshirpour Y, Sanders M, Brewer M, Zhu Q, “Potential role of coregistered photoacoustic and ultrasound imaging in ovarian cancer detection and characterization”, Transl Oncol. 2011, Feb 1;4(1):29-37

Gamelin J, Aquirre A, Zhu Q, “Fast, limited-data photoacoustic imaging for multiplexed systems using a frequency-domain estimation technique”, Med. Phys. 38 (3) 1-16, March 2011

Kumavor PD, Xu C, Aguirre A, Gamelin J, Ardeshipour Y, Tavakoli B, Zanganeh S, Alqasemi U, Yang Y, Zhu Q, “Target Detection and Quantification using a Hybrid Hand-held Diffuse Optical Tomography and Photoacoustic Tomography System”, J. Biomed. Optics, April 2011, 16(4): 046010(1-12)

Ardeshirpour Y, Biswal N, Aguirre A, Zhu Q, “Artifact reduction method in ultrasound-guided diffuse optical tomography using exogenous contrast agents”, J. Biomed. Optics, April 2011, 16(4) 046015(1-11)

Tavakoli B, Zhu Q, “Depth correction algorithm that improves optical quantification of large breast lesions imaged by diffuse optical tomography”, J. Biomed. Optics, May 2011, 16(5), 056002

Xu Z, Zhu Q, Wang LV, “In vivo photoacoustic tomography of mouse cerebral edema induced by cold injury”, J. Biomed. Optics, June 2011, 16(6), 066020(1-4)

Biswal N, Pavlik C, Smith MB, Aguirre A, Xu Y, Zanganeh S, Kuhn LT, Claffey KP, Zhu Q, “Imaging tumor hypoxia by near-infrared fluorescence tomography”, J. Biomed. Optics, June 2011, 16(6)

Yang Y, Biswal N, Wang T, Kumavor PD, Karimeddini M, Vento J, Sanders M, Brewer M, Zhu Q, “Potential role of a hybrid intraoperative probe based on OCT and positron detection for ovarian cancer detection and characterization”, Biomedical Optics Express 2011 2(7), 1918-1930

Xu Y, Xu C, Zhu Q, “Clustered targets imaged by optical tomography guided by ultrasound”, J. Biomed. Optics, 16(7), 076018 (1-16)

Kumavor PD, Tavakoli B, Donkor E, Zhu Q, “Time-gating scheme based on a photodiode for single-photon counting”, Optics Letters, Vol. 36, Iss. 13, pp. 2501-2503 (2011)

Chen Y, Otis L, Zhu Q, “Polarization Memory Effect in Optical Coherence Tomography and Dental Imaging Application”, J. BioMed. Optics., 16(8): August 2011

Yang Y, Li X, Wang T, Kumavor PD, Aguirre A, Shung K, Zhou Q, Sanders M, Brewer M, Zhu Q, “Integrated Optical Coherence Tomography, Ultrasound and Photoacoustic Imaging for Ovarian Tissue Characterization”, Biomedical Optics Express 2011 Sep 1;2(9):2551-61

Xia J, Guo Z, Maslov K, Aguirre A, Zhu Q, Percival C, Wang LV, “Three-dimensional photoacoustic tomography based on the focal-line concept”, J Biomed Opt. 2011 Sep;16(9):090505

Yang Y, Wang T, Biswal N, Wang X, Sanders M, Brewer M, Zhu Q, “Optical Scattering Coefficient Estimated by OCT Correlates with Collagen Content in Ovarian Tissue”, J. Biomed. Optics Letters, September 2011 Vol. 16(9); 090504(1:3)

Biswal N, Xu Y, Zhu Q, “Imaging tumor oxyhemoglobin and deoxyhemoglobin concentrations with ultrasound-guided diffuse optical tomography”, Technology in cancer research and treatment, Technol Cancer Res Treat. 2011 Oct;10(5):417-29

2005-2010

2010

Li C, Aguirre A, Gamelin J, Maurudis A, Zhu Q, Wang LV, “Real-time photoacoustic tomography of cortical hemodynamics in small animals”, J. Biomed. Optics. January/February 2010, 15(1): (1-3)

Biswal N, Gamelin J, Yuan B, Backer M, Backer J, Zhu Q, “Fluorescence imaging of vascular endothelial growth factor in tumors for mice embedded in a turbid medium”, J. Biomed. Optics. January/February 2010, 15(1):016012 (1-11)

Xu C, Zhu Q, “Light shadowing effect of large breast lesions imaged by optical tomography in reflection geometry”, J. Biomed. Optics. May/June, 2010, 15 (3):036003

Ardeshirpour Y, Zhu Q, “An optical tomography method that accounts for the tilted chest wall in breast imaging”, J. Biomed. Optics. July/August 2010, 15 (4):041515

Tavakoli B, Kumavor PD, Aguirre A, Zhu Q, “Effect of Ultrasound Transducer Face Reflectivity on the Light Fluence inside a Turbid Medium in Photoacoustic Imaging”, J. Biomed. Optics. July/August 2010, 15(4): 046003 (1-10)

Zhu Q, Hegde P, Ricci A, Kane M, Cronin C, Ardeshirpour Y, Xu C, Aguirre A, Kurtzman S, Deckers P, and Tannenbaum S, “The potential role of optical tomography with ultrasound localization in assisting ultrasound diagnosis of early-stage invasive breast cancers”, Radiology, Volume 256: Number 2-August 2010, 367-378

Pavlik C, Biswal N, Gaenzler FC, Morton MD, Kuhn LT, Claffey KP, Zhu Q, Smith MB, “Synthesis and Fluorescent Characteristics of Imidazole-Indocyanine Green Conjugates”, Dyes and Pigments 2010, 89 (2011) 9-15

Yan X, Zhu Q, “Imaging heterogeneous absorption distribution of advanced breast cancer by optical tomography”, J. Biomed. Optics. Nov/Dec 2010, 15(6), 066007(1-17)

2009

Gamelin J, Aguirre A, Maurudis A, Huang F, Castillo D, Wang LV, Zhu Q, “Design and characterization of an array-based photoacoustic tomographic system for small animal imaging”, In Photoacoustic imaging and Spectroscopy Edited by L.V. Wang, CRC Press, 2009

Yang X, Maurudis A, Gamelin J, Aguirre A, Zhu Q, Wang LV, “Photoacoustic tomography of small Animal Brain with a curved array transducer”, J. Biomed. Opt. 2009, 14: 054007 (1-7)

Aguirre A, Puyun G, Gamelin J, Yan S, Sanders M, Brewer M, Zhu Q, “Co-registered 3-D ultrasound and photoacoustic imaging system for ovarian tissue characterization”, J. Biomed. Opt. 2009 Sept., 14(5):054014 (1-9)

Gamelin J, Yang Y, Biswal N, Chen Y, Yan S, Zhang X, Karemeddini M, Brewer M, Zhu Q, “A prototype hybrid intraoperative probe for ovarian cancer detection”, Optics Express 2009, 17(9):7245-7258

Gamelin J, Maurudis A, Aguirre A, Huang F, Guo P, Wang LV, Zhu Q, “A real-time photoacoustic tomography system for small animals”, Optics Express 2009, 17(13):10489-10498

Ardeshirpour Y, Huang MM, Zhu Q, “Effect of the chest wall on breast lesion reconstruction”, J. Biomed. Optics, July/August 2009, 14(4): 044005 (1-14)

2008

Gamelin J, Aguirre A, Maurudis A, Huang F, Castillo D, Wang VL, Zhu Q, “Curved array photoacoustic tomographic system for small animal imaging”, J. Biomed. Optics, May/June, 2008 13(2): 024007: 1-10

Yuan BY, Gamelin J Zhu Q, “Mechanisms of the ultrasonic modulation of fluorescence in turbid media”, J. Applied Physics Nov 2008, 104, 103102 (1-14)

Jiang Z, Zhu Q, Piao DQ, “Minimization of geometric-beam-broadening in a grating based time-domain delay line for optical coherence tomography application”, J. Opt. Soc. Am A 2008, 24(12):3808:3818

Xu C, Yuan B, Zhu Q, “Optimal probe design for breast imaging using near infrared diffused light”, J. Biomed. Optics, July/August 2008, 13(4): 044002 (1-10)

Zhu Q, Tannenbaum S, Hegde P, Kane M, Xu C, Kurtzman SH, “Noninvasive monitoring of breast cancer during neoadjuvant chemotherapy using optical tomography with ultrasound localization”, Neoplasia, October 2008, 10 (10): 1028-1040.

Xu C, Das M, Ardeshirpour Y, Zhu Q, “An image reconstruction method for a two-layer tissue structure accounts for chest-wall effects in breast imaging”, J. Biomed. Optics November/December 2008, 13(6): 064029 (1-13)

2007

Chen Y, Willett P, Zhu Q, “Frequency tracking in optical Doppler tomography using an adaptive notch filter”, J. Biomedical Optics, Jan/Feb 2007,12(1): 014018(1-9)

Zhu Q, Tannenbaum S, Kurtzman S, “Optical Tomography with Ultrasound Localization for Breast Cancer Diagnosis and Treatment Monitoring”, Surgical Oncology Clinics of North America (2007)

2006

Das M, Xu C, Zhu Q, “Analytical solution for light propagation in a two-layer tissue structure with a tilted interface for breast imaging”, Applied Optics July 2006, 45(20):5027-5036.

Zhu Q, Xu C, Guo PY, Aquirre A, Yuan B, Huang F, Castilo D, Gamelin J, Tannenbaum S, Kane M, Hedge P, Kurtzman S, “Optimal probing of optical contrast of breast lesions of different size located at different depths by US localization”, Technology in Cancer Research & Treatment, August 2006,5 (4): 365-380.

Yuan B, Zhu Q, “Separately reconstructing the structural and functional parameters of a fluorescent inclusion embedded in a turbid medium”, Optics Express, August 2006, 14 (16):7172-7187

2005

Xu C, Zhu Q, “Estimation of chest wall induced diffused wave distortion with the assistance of ultrasound”, Applied Optics, 2005, 44(20): 4255-4264.

Zhu Q, Kurtzman S, Hegde P, Tannenbaum S, Kane M, Huang MM, Chen NG, Jagjivan B, Zarfos K, “Utilizing optical tomography with ultrasound localization to image heterogeneous hemoglobin distribution in large breast cancers”, Neoplasia, 2005, 7(3): 263-270.

Zhu Q, “Optical tomography with ultrasound localization: initial clinical results and technical challenges”, Technology in Cancer Research & Treatment, June 2005, 4(3): 235-244

Zhu Q, Cronin E, Currier A, Vine HS, Huang MM, Chen NG, Xu C, “Benign versus Malignant Breast Masses: Optical Differentiation using US-Guide Optical Imaging Reconstruction”, Radiology, OCT 2005, 237:57:66

Piao DQ, Zhu Q, “Direct Bi-directional Angle-insensitive Imaging of the Flow Signal Intensity In Doppler Optical Coherence Tomography”, Applied Optics, 2005, 44(3): 348-357

Piao DQ, Sadeghi MM, Zhang JS, Chen Y, Sinusas AJ, Zhu Q, “Hybrid positron detection and optical coherence tomography system: Design, calibration and experimental validation with rabbit atherosclerotic models”, J. Biomed. Optics, July/August 2005. 044010 10(4)

Chen Y, Otis L, Piao DQ, Zhu Q, “Characterization of dentin, enamel and carious lesions by a polarization-sensitive optical coherence tomography system”, Applied Optics, 2005, 44(11): 2041-2048

2000-2004

2004

Huang MM, Zhu Q, “A Dual-mesh optical tomography reconstruction method with depth correction using a priori ultrasound information”, Applied Optics 2004, 43(8):1654-1662

Chen NG, Huang M, Zia HJ, Piao DQ, Cronin E, Zhu Q, “Portable near infrared diffusive light imager for breast cancer detection”, J. Biomed. Optics, May/June 2004, 504-510

Huo Y, Bansal R, Zhu Q, “Modeling of noninvasive microwave characterization of breast tumors”, IEEE Transactions on Biomedical Engineering, 2004, 51(7): 1089-1094

Otis L, Piao DQ, Gibson C, Zhu Q, “Quantifying labial blood flow using optical Doppler tomography”, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2004, 98(2), 189-194

Piao DQ, Zhu Q, “Power-efficient grating-based scanning optical delay line: time-domain configuration”, Electronics Letters 2004, 40(2):97-99

Yan SK, Piao DQ, Chen Y, Zhu Q, “A DSP-based real-time optical Doppler tomography system”, Journal of Biomedical Optics, May/June 2004, 9(3):454-463.

Yuan BY, Chen G, Zhu Q, “Emission and absorption properties of indocyanine green in a intralipid solution”, J. Biomedical optics, May/June 2004, 497-503

2003

Zhu Q, Chen NG, Kurtzman S, “Imaging tumor angiogenesis by use of combined near infrared diffusive light and ultrasound”, Optics Letters, March 2003, 28(5): 337-339

Huang MM, Xie TQ, Chen NG, Zhu Q, “Simultaneous reconstruction of absorption and scattering maps with ultrasound localization: feasibility study using transmission geometry”, Applied Optics, 2003, 42(19): 4102-4114

Chen NG, Zhu Q, “Time-resolved diffusive optical imaging using pseudo-random bit sequences”, Optics Express 2003, 11(25), 3445-3454

Zhu Q, Huang MM, Chen NG, Zarfos K, Jagjivan B, Kane M, Hedge P, Kurtzman S, “Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: initial clinical results of 19 cases”, Neoplasia, 2003, 5(5): 379-388

Piao DQ, Zhu Q, “Quantitation of Doppler angle and Flow Velocity mapping by Combining Doppler Shift and Doppler Bandwidth Measurements in Optical Doppler Tomography”, Applied Optics, 2003, 42(25): 5158:5172

Piao DQ, Otis L, Zhu Q, “Doppler angle and Flow Velocity mapping by Combining Doppler Shift and Doppler Bandwidth Measurements in Optical Doppler Tomography”, Optics Letters, July 2003, 28(13): 1120-1123

Zhu Q, Piao DQ, Sadeghi M, Sinusas A, “Simultaneous optical coherence tomography imaging and beta particle detection”, Optics Letters, Sept 2003, 28(18): 1704-1706

2002

Chen NG, Zhu Q, “Time-resolved optical measurements with spread spectrum excitation”, 27(4): 252-254, Oct 2002

Chen NG, Zhu Q, “Characterization of small absorbers inside turbid media”, Optics Letters, 27 (4): 252, Feb 2002

Chen NG, Zhu Q, “Rotary mirror array for high speed optical coherence tomography”, Optics Letters, (27) No.8, 607-609, April 2002.

Piao DQ, Otis L, Dutta N, Zhu Q, “Quantitative assessment of flow velocity estimation algorithms for optical Doppler tomography imaging”, Applied Optics, (41) No.29,6118-6127, October 2002

2001

Zhu Q, Chen NG, Piao DQ, Guo PY, Ding XH, “Design of near infrared imaging probe with the assistance of ultrasound localization”, Applied Optics, (40) No. 19, 3288-3303, July 2001

Piao DQ, Zhu Q, Datta N, Yan SK, Otis L, “Cancellation of coherent artifacts in optical coherence tomography imaging”, Applied Optics, (40) No. 31, 5124-5131, November 2001

Chen NG, Guo PY, Yan SK, Piao DQ, Zhu Q, “Simultaneous near infrared diffusive light and ultrasound imaging”, Applied Optics, December, 40(34): 6367-6380, 2001

Zhu Q, Chen NG, Guo PY, Yan SK, Piao DQ, “Near Infrared Diffusive Light Imaging with Ultrasound Localization, OSA Optics and Photonics News”, Optics in 2001, 12:31, December 2001

2000

Zhu Q, Conant E, Chance B, “Optical imaging as an adjunct to sonograph in differentiating benign from malignant breast lesions”, journal of Biomedical Optics, 5(2): 229-236, 2000

Before 2000

Zhu Q, Sullivan D, Chance B, Dambro T, “Combined ultrasound and near infrared diffusive light imaging”, IEEE Transactions on Ultrasonic, Ferroelectrics and Frequency Control, 46(3): 665-678, 1999

Zhu Q, Durduran T, Holboke M, Ntziachristos V and Yodh A., “Imager that combines near infrared diffusive light and ultrasound”, Optics letters, 24(15): 1050-1053, Aug 1999

Zhu Q, Steinberg BD, “Large-transducer measurements of wavefront distortion in the female breast”, Ultrasonic Imaging 14: 276-299, 1992

Zhu Q, Steinberg BD, “Wavefront amplitude distortion and image sidelobe levels – Part I: theory and computer simulation”, IEEE Transactions on Ultrasonic, Ferroelectrics and Frequency Control (40): 747-753, 1993

Zhu Q, Steinberg BD and Arenson R, “Wavefront amplitude distortion and image sidelobe levels -Part II: In vivo experiments”, IEEE Transactions on Ultrasonic, Ferroelectrics and Frequency Control (40):754-761, 1993

Zhu Q, Steinberg, BD, “Wavefront amplitude distribution in the female breast”, J. Acoust. Soc. Am. (46): 1-9, 1994

Hinkelman LM, Liu D-L, Zhu Q, Steinberg BD, and Waag RC, “Measurement and correction of ultrasonic pulse distortion produced by the human breast”, J. Acoust. Soc. Am. (97): 1958-1969, 1995

Zhu Q, Steinberg BD, Arenson R, “Correlation distance measurements of the female breast”, J. Acoust. Soc. Am, (98): 694-705, 1995

Zhu Q, Steinberg BD, “Deaberration of incoherent wavefront Distortion: An Approach toward Inverse Filtering”, IEEE Transactions on Ultrasonic, Ferroelectrics and Frequency Control, 40(3): 575-589, 1997

Zhu Q, Steinberg BD, “Modeling and correction of incoherent wavefront distortion”, Special issue of I’nal J. Sci. Tech. Imaging, Wiley, (03): 322:335, 1997